UNIVERSITY OF WISCONSIN River Falls

Faculty and Staff

Martins, Alessandro

Aless

Assistant Professor

Email:

Education:

Ph.D., Physical Chemistry, 2013, State University of Maringá, Brazil. 

Thesis: Preparation, characterization, and application of polymeric materials based on chitosan and N,N,N-trimethyl chitosan, Adviser: Professor Edvani C. Muniz 

B.S., Chemistry, 2009, State University of Maringá, Brazil. 

Courses Taught:

CHEM 111 General Chemistry I 

CHEM 112 General Chemistry II 

CHEM 341 Chemical Thermodynamics and Kinetics 

CHEM 342 Molecular Structure & Spectroscopy  

CHEM 311 Polymer Chemistry 

Research Interests:

  • Polymers, biopolymers, hydrogels, and composite materials; 
  • Nanoparticles and drug delivery;  
  • Electrospinning and nanofibers;  
  • Layer-by-layer and thin films;  
  • Scaffolds, wound dressings, and antimicrobial coatings;  
  • Cytocompatibility; blood-compatibility; mammalian cells. 

Publications:

  1. K.B. Rufato, F.R. Veregue, R. de Paula Medeiro, C.B. Francisco, P.R. Souza, K.C. Popat, M.J. Kipper, A.F. Martins, Electrospinning of poly (vinyl alcohol) and poly (vinyl alcohol)/tannin solutions: A critical viewpoint about crosslinking, Materials Today Communications (2023). https://doi.org/10.1016/j.mtcomm.2023.106271.  
 
  1. O.A. Silva, M.G. Pellá, R.M. Sabino, K.C. Popat, M.J. Kipper, A.F. Rubira, H.D.M. Follmann, R. Silva, A.F. Martins. Carboxymethylcellulose hydrogels crosslinked with keratin nanoparticles for efficient prednisolone delivery. International Journal of Biological Macromolecules (2023). https://doi.org/10.1016/j.ijbiomac.2023.124497.  
  2. P.R. Souza, B.H. Vilsinski, A.C. de Oliveira, S.B.R. Berton, H.S. Schrekker, E. Radovanovic, M.J. Kipper, A.F. Martins, E.C. Muniz, Poly(ethylene terephthalate) films coated with antimicrobial gelatin/chondroitin sulfate polyelectrolyte multilayers containing ionic liquids, Progress in Organic Coatings (2022). https://doi.org/10.1016/j.porgcoat.2022.106997  
 
  1. R. Maia Sabino; A.F Martins; Matt J Kipper; Ketul C. Popat "Improved In Vitro Endothelialization on Nanostructured Titania with Tannin/glycosaminoglycan-based Polyelectrolyte Multilayers, In Vitro Models (2022). https://doi.org/10.1007/s44164-022-00024-x 
  2. E. Bonifácio, D.P. Facchi, P.R. Souza, J.P. Monteiro, K.C. Popat, M.J. Kipper, A.F. Martins, A tannin-polymer adsorbent created from the freezing-thawing method for removal of metal-complex acid black 172 and methylene blue from aqueous solutions, Journal of Molecular Liquids (2022). https://doi.org/10.1016/j.molliq.2022.118682  
 
  1. D.P. Facchi, S.P. Facchi, P.R. Souza, E.G. Bonafé, K.C. Popat, M.J. Kipper, A.F. Martins, Composite filter with antimicrobial and anti-adhesive properties based on electrospun poly(butylene adipate-co-terephthalate)/poly(acid lactic)/Tween 20 fibers associated with silver nanoparticles, Journal of Membrane Science (2022). https://doi.org/10.1016/j.memsci.2022.120426  
 
  1. D.A. de Almeida, A.C. de Oliveira, R.S. Klein, E.G. Bonafé, M.J. Kipper, A.F. Martins, J.P. Monteiro, κ-Carrageenan-capped core-shell gold@silver nanoparticles: Optical sensors for reactive oxygen species, Nano-Structure & Nano-Objects (2022) https://doi.org/10.1016/j.nanoso.2022.100861  
 
  1. S. Iqbal, A.F. Martins, M. Sohail, Z. Jingjing, D. Qi, L. Muhan, Z. Zhao, Synthesis and Characterization of Poly (β-amino ester) and Applied PEGylated and non-PEGylated Poly (β-amino ester)/plasmid DNA Nanoparticles for Efficient Gene Delivery, Frontiers in Pharmacology (2022). https://doi.org/10.3389/fphar.2022.854859  
 
  1. L. Del C. B. Araújo, H.K. de Matos, D.P. Facchi, D.A. de Almeida, B.M.G. Gonçalves, J.P. Monteiro, A.F. Martins, E.G. Bonafé, International Journal of Biological Macromolecules (2022). https://doi.org/10.1016/j.ijbiomac.2021.11.014 
 
  1. O.A. Silva, M.G. Pellá, K.C. Popat, M.J. Kipper, A.F. Rubira, A.F. Martins, H.D.M. Follmann, R. Silva, Rod-shaped keratin nanoparticles extracted from human hair by acid hydrolysis as photothermally triggered berberine delivery system, Advanced Powder Technology, (2022). https://doi.org/10.1016/j.apt.2021.11.005 
 
  1. R.S. Klein, E.G. Bonafé, A.F. Martins, J. P. Monteiro, Trans-resveratrol electrochemical detection using portable device based on unmodified screen-printed electrode, Journal of Pharmaceutical and Biomedical Analysis (2022). https://doi.org/10.1016/j.jpba.2021.114399 
  2. R.M. Sabino, G. Mondini, M.J. Kipper, A.F. Martins, K.C. Popat, Tanfloc/heparin polyelectrolyte multilayers improve osteogenic differentiation of adipose-derived stem cells on titania nanotube surfaces, Carbohydrate Polymers (2021). https://doi.org/10.1016/j.carbpol.2020.117079 
 
  1. A.C. de Oliveira, G.R.F de Lima, R.S. Klein, P.R. Souza, F.P. Garcia, C.V. Nakamura, A.F. Martins, Thermo-and pH-responsive chitosan/gellan gum hydrogels incorporated with the β-cyclodextrin/curcumin inclusion complex for efficient curcumin delivery, Reactive & Functional Polymers (2021). https://doi.org/10.1016/j.reactfunctpolym.2021.104955 
 
  1. A.C de Oliveira, P.R Souza, B.H. Vilsinski, M.E.G Winkler, M.L. Bruschi, E. Radovanovic, E.C. Muniz, W. Caetano, A.J.M. Valente, A.F. Martins, Thermo- and pH-Responsive Gelatin/Polyphenolic Tannin/Graphene Oxide Hydrogels for Efficient Methylene Blue Delivery, Molecules (2021). https://doi.org/10.3390/molecules26154529 
 
  1. P.R. Souza, A.C. de Oliveira, B.H. Vilsinski, M.J. Kipper, A.F. Martins, Polysaccharide-based materials created by physical processes: From preparation to biomedical applications, Pharmaceutics (2021). https://doi.org/10.3390/pharmaceutics13050621 
 
  1. K.B. Rufato, P.R. Souza, A.C. de Oliveira, S.B.R. Berton, R.M. Sabino, E.C. Muniz, K.C. Popat, E. Radovanovic, M.J. Kipper, A.F. Martins, Antimicrobial and cytocompatible chitosan, N,N,N-trimethyl chitosan, and tanfloc-based polyelectrolyte multilayers on gellan gum films, International Journal of Biological Macromolecules (2021). https://doi.org/10.1016/j.ijbiomac.2021.04.138        
 
  1. A.M.S. Plath, S.P. Facchi, P.R. Souza, R.M. Sabino, E. Corradini, E.C. Muniz, K.C. Popat, L.C. Filho, M. J. Kipper, A.F. Martins, Zein supports scaffolding capacity toward mammalian cells and bactericidal and anti-adhesive properties on poly(ε-caprolactone)/zein electrospun fibers, Materials Today Chemistry, (2021) 100465. https://doi.org/10.1016/j.mtchem.2021.100465  
 
  1. L.C. Bonkovoski, B.H. Vilsinski, M.R. Panice, C.S. Nunes, G. Braga, Danielle Lazarin-Bidóia, C.V. Nakamura, A.F. Martins, E.C. Muniz, Cytocompatible drug delivery devices based on poly[(2-dimethylamino) ethyl methacrylate]/chondroitin sulfate polyelectrolyte complexes prepared in ionic liquids, Journal of Drug Delivery Science and Technology, (2021), https://doi.org/10.1016/j.jddst.2021.102520.  
 
  1. P. R. Souza, B. H. Vilsinski, A. C de Oliveira, S. B. R. Berton, C. S. Nunes, M. J. Kipper, H. S. Schrekker, A.F. Martins, E. C. Muniz, Chitosan/heparin blends in ionic liquid produce polyelectrolyte complexes that quickly adsorb citrate-capped silver nanoparticles, forming bactericidal composites, Journal of Molecular Liquids (2021) 115548. https://doi.org/10.1016/j.molliq.2021.115548  
 
  1. S.B.R Berton, E.G. Bonafé, G.A.M. de Jesus, R. da Silveira, J.V. Visentainer, A.F Martins, M. Matsushita, Sensitivity of phenolic compounds evaluated by a new approach of analytical methods, Chemical Papers (2021). https://doi.org/10.1007/s11696-021-01698-5 
 
  1. B. R. Machado, S. P. Facchi, A. C de Oliveira, C. S. Nunes, P. R. Souza, B. H. Vilsinski, K. C. Popat, M. J. Kipper, E. C. Muniz, A.F. Martins, Bactericidal Pectin/Chitosan/Glycerol Films for Food Pack Coatings: A Critical Viewpoint. International Journal of Molecular Science (2020). https://doi.org/10.3390/ijms21228663 
 
  1. I. P. A. F. Souza, L. H. S. Crespo, L. Spessato, S. A. R. Melo, A.F. Martins, A. L. Cazetta, V. C. Almeida, Optimization of thermal conditions of sol-gel method for synthesis of TiO2 using RSM and its influence on photodegradation of tartrazine yellow dye, Journal of Environmental Chemical Engineering (2020). https://doi.org/10.1016/j.jece.2020.104753. 
 
  1. E.T.O Bezerra, S. B. R. Berton, A. C. de Oliveira, P. R. Souza, C. F. Vecchi, M. L. Bruschi, B. H. Vilsinski, A.F Martins, The cooling of blends in water supports durable, thermo-responsive, and porous gelatin-polyphenolic tannin assemblies with antimicrobial activities. Materials Today Communications (2020). https://doi.org/10.1016/j.mtcomm.2020.101883  
 
  1. B.H. Vilsinski, P. R. Souza, A. C de Oliveira, M.C. César Filho, A. J. M. Valente, E. C. Muniz, O. Borges, A. P. Gerola, W. Caetano, A.F. Martins, Photophysics and drug delivery behavior of methylene blue into Arabic-gum based hydrogel matrices. Materials Today Communications (2020). https://doi.org/10.1016/j.mtcomm.2020.101889  
 
  1. P. R. Souza, B. H. Vilsinski, C. S Nunes, L. C. Bonkovoski, F. Garcia, C. V. Nakamura, W. Caetano, A. J. M. Valente, A.F. Martins, E. C. Muniz. Application of a polyelectrolyte complex based on biocompatible polysaccharides for colorectal cancer inhibition. Carbohydrate Research (2020). https://doi.org/10.1016/j.carres.2020.108194. 
 
  1. S. B. R. Berton, M. P. Ferreira, E. A. Canesin, R. M. Suzuki, A. F. Martins, E. G. Bonafé, M. Matsushita Sequência didática para a promoção de estudo prático e multidisciplinar com materiais acessíveis. Química Nova (2020). http://dx.doi.org/10.21577/0100-4042.20170506 
 
  1. C. de Lima Barizão, M.I Crepaldi, O. de Oliveira S. junior, A.C de Oliveira, A.F Martins, P.S Garcia, E.G Bonafé. Biodegradable films based on commercial k-carrageenan and cassava starch to achieve low production costs, International Journal of Biological Macromolecules, (2020) 582-590. https://doi.org/10.1016/j.ijbiomac.2020.09.150 
 
  1. L.Z Silva, M.R Mauricio, P.G Dubiela, A.F Martins, A.F Rubira. Star-shaped amino-functionalized poly(glycerol methacrylate)-stabilized gold nanoparticle composites with catalytic activity for reduction of 4-nitrophenol, Journal of Molecular Liquids, (2020). https://doi.org/10.1016/j.molliq.2020.114119 
 
  1. A.G.B. Pereira, F.H.A Rodrigues, A.T. Paulino, A.F. Martins, A.R. Fajardo. Recent advances on composite hydrogels designed for the remediation of dye-contaminated water and wastewater: a review, Journal of Cleaner Production, (2020). https://doi.org/10.1016/j.jclepro.2020.124703 
 
  1. D.P. Facchi, P.R. Souza, V.C. Almeida, E.G Bonafé, A.F Martins, Optimizing the Ecovio® and Ecovio®/zein solution parameters to achieve electrospinnability and provide thin fibers, Journal of Molecular Liquids, (2020). https://doi.org/10.1016/j.molliq.2020.114476 
 
  1. K.J.P. Pavezi, A. Rocha, E.G. Bonafé, A.F. Martins, Electrospinning-electrospraying of poly(acid lactic) solutions in binary chloroform/formic acid and chloroform/acetic acid mixtures, Journal of Molecular Liquids, (2020). https://doi.org/10.1016/j.molliq.2020.114448 
 
  1. A.B. da Silva, K.B. Rufato, A.C. de Oliveira, P.R Souza, E.P. da Silva, E.C. Muniz, B.H. Vilsinski, A.F. Martins, Composite materials based on chitosan/gold nanoparticles: From synthesis to biomedical applications, International Journal of Biological Macromolecules, (2020). https://doi.org/10.1016/j.ijbiomac.2020.06.113 
 
  1. J.G. Martins, D.P. Facchi, S.B.R. Berton, C.S. Nunes, M. Matsushita, E.G. Bonafé, K.C. Popat, V.C. Almeida, M.J. Kipper, A.F. Martins, Removal of Cu(II) from aqueous solutions imparted by a pectin-based film: Cytocompatibility, antimicrobial, kinetic, and equilibrium studies, International Journal of Biological Macromolecules, (2020). https://doi.org/10.1016/j.ijbiomac.2020.02.220 
 
  1. S.P. Facchi, A.C. de Oliveira, E. de Oliveira T. Bezerra, J. Vlcek, M. Hedayati, M.M. Reynolds, M.J. Kipper, A.F. Martins, Polycationic condensed tannin/polysaccharide-based polyelectrolyte multilayers prevent microbial adhesion and proliferation, European Polymer Journal, (2020). https://doi.org/10.1016/j.eurpolymj.2020.109677 
 
  1. P.C.F. da Câmara, L.Y.C. Madruga, R.M. Sabino, J. Vlcek, R.C. Balaban, K.C. Popat, A.F. Martins, M.J. Kipper, Polyelectrolyte multilayers containing a tannin derivative polyphenol improve blood compatibility through interactions with platelets and serum proteins, Materials Science & Engineering C, (2020). https://doi.org/10.1016/j.msec.2020.110919 
 
  1. M.V. Recanello, E.K. Lenzi, A.F. Martins, Q. Li, R.S. Zola, Extended adsorbing surface reach and memory effects on the diffusive behavior of particles in confined systems, International Journal of Heat and Mass Transfer, (2020). https://doi.org/10.1016/j.ijheatmasstransfer.2020.119433 
 
  1. D.A. de Almeida, R.M. Sabino, P.R. Souza, E.G. Bonafé, S.A.S. Venter, K.C. Popat, A.F. Martins, J.P. Monteiro, Pectin-capped gold nanoparticles synthesis in-situ for producing durable, cytocompatible, and superabsorbent hydrogel composites with chitosan, International Journal of Biological Macromolecules, (2020). https://doi.org/10.1016/j.ijbiomac.2020.01.058 
 
  1. L. Spessato, A.L. Cazetta, S. Melo, O. Pezoti, J. Tami, A. Ronix, J.M. Fonseca, A.F. Martins, T.L. Silva, V.C. Almeida, Synthesis of superparamagnetic activated carbon for paracetamol removal from aqueous solution, Journal of Molecular Liquids, (2020). https://doi.org/10.1016/j.molliq.2019.112282 
 
  1. J.A. da Cruz, A.B. da Silva, B.B.S. Ramin, P.R. Souza, K.C. Popat, R.S. Zola, M.J. Kipper, A.F. Martins, Poly(vinyl alcohol)/cationic tannin blend films with antioxidant and antimicrobial activities, Materials Science & Engineering C, (2020). https://doi.org/10.1016/j.msec.2019.110357 
 
  1. A.F. Martins, J. Vlcek, T. Wigmosta, M. Hedayati, M.M. Reynolds, K.C. Popat, M.J. Kipper, Chitosan/iota-carrageenan and chitosan/pectin polyelectrolyte multilayer scaffolds with antiadhesive and bactericidal properties, Applied Surface Science, (2020). https://doi.org/10.1016/j.apsusc.2019.144282 
 
  1. R.M. Sabino, K. Kauk, L.Y.C. Madruga, M.J. Kipper, A.F. Martins, K.C Popat, Enhanced hemocompatibility and antibacterial activity on titania nanotubes with tanfloc/heparin polyelectrolyte multilayers, Journal of Biomedical Materials Research Part A, (2020). https://doi.org/10.1002/jbm.a.36876 
 
  1. S.B.R. Berton, G.A.M. de Jesus, R.M. Sabino, J.P. Monteiro, S.A.S. Venter, M.L. Bruschi, K.C. Popat, M. Matsushita, A.F. Martins, E.G. Bonafé, Properties of a commercial κ-carrageenan food ingredient and its durable superabsorbent hydrogels, Carbohydrate Research, (2020). https://doi.org/10.1016/j.carres.2019.107883 
 
  1. S.B.R Berton, M. Cabral, G. de Jesus, M. Sarragiotto, E. Pilau, A.F. Martins, E.G. Bonafé, M. Matsushita, Ultra-high-performance liquid chromatography supports a new reaction mechanism between free radicals and ferulic acid with antimicrobial and antioxidant activities, Industrial Crops & Products, (2020). https://doi.org/10.1016/j.indcrop.2020.112701 
 
  1. A.C de Oliveira, R.M. Sabino, P.R. Souza, E.C. Muniz, K.C Popat, M.J. Kipper, R.S Zola, A.F Martins. Chitosan/gellan gum ratio content into blends modulates the scaffolding capacity of hydrogels on bone mesenchymal stem cells, Materials Science & Engineering C, (2020). https://doi.org/10.1016/j.msec.2019.110258  
 
  1. P. da Câmara, R. Balaban, H. Mohammadhasan, P. Ketul, A.F. Martins, M. J. Kipper, Novel cationic tannin/glycosaminoglycan-based polyelectrolyte multilayers promote stem cells adhesion and proliferation. RSC Advances (2019), 25836-25846. 10.1039/C9RA03903A  
 
  1. B.B.S. Ramin, K.B. Rufato, R.M. Sabino, K.C. Popat, M.J. Kipper, A.F. Martins, E.C. Muniz, Chitosan/iota-carrageenan/curcumin-based materials performed by precipitating miscible solutions prepared in ionic liquid. Journal of Molecular Liquids (2019). https://doi.org/10.1016/j.molliq.2019.111199  
 
  1. B.R. Machado, S.B. Roberto, E.G. Bonafe. S.E.A. Camargo, C.H.R. Camargo, K.C. Popat, M.J. Kipper, A.F. Martins, Chitosan Imparts Better Biological Porperties for Poly(ε-caprolactone) Electrospun Membranes Than Dexamethasone. Journal of the Brazilian Chemical Society (2019). https://doi.org/10.21577/0103-5053.20190077  
 
  1. K.B. Rufato, V.C. Almeida, M.J. Kipper, A.F. Rubira, A.F. Martins, E.C. Muniz, Polysaccharide-based adsorbents prepared in ionic liquid with high performance for removing Pb(II) from aqueous systems. Carbohydrate Polymers (2019). https://doi.org/10.1016/j.carbpol.2019.03.095  
 
  1. A.C. de Oliveira, B. H. Vilsinski, E. G. Bonafe, J. P. Monteiro, M. J. Kipper, A.F. Martins. Chitosan content modulates durability and structural homogeneity of chitosan-gellan gum assemblies. International Journal of Biological Macromolecules (2019). https://doi.org/10.1016/j.ijbiomac.2019.01.110  
 
  1. A.P. Lopes, P.R, Souza, E.G. Bonafe, J.V. Visentainer, A.F. Martins, E.A. Canesin Purified glycerol is produced from the frying oil transesterification by combining a pre-purification strategy performed with condensed tannin polymer derivative followed by ionic exchange. Fuel Processing Technology (2019). https://doi.org/10.1016/j.fuproc.2019.01.014