Varghese, Tony


Tony Varghese

Professor - College of Business and Economics

Computer Science and Information Systems
Office: 127c South Hall
Phone: 715-425-3335



Ph.D. University of Minnesota, Minneapolis, MN, Biomedical Engineering, 1992

M.S. University of Minnesota, Minneapolis, MN, Electrical Engineering, 1987

B.S. University of Wisconsin Platteville, Platteville, WI, Electrical Engineering, 1983

Courses Taught:

Advanced Computer Networks

C++ Programming

Computer Graphics

Data Structures and Algorithms

Introduction to Bioinformatics

Object-Oriented Programming

Operating Systems

Operating Systems Programming

Programming I

Programming II

Software Engineering

Special Topics: Computer Science

Research Interests:

My research involves the simulation of biological systems, specifically cellular electrophysiology. I use the tools of Mathematical Modeling, Numerical Methods for Differential Equations, and High-Performance Computing to address research problems in the area of Cellular Electrophysiology. With the help of numerous collaborators in academia and industry, I also use the techniques of Cell culture, Immunochemistry, and Molecular Biology: PCR, siRNA.


Articles in Journals
  • Zhao, J. T., Hill, A. P., Varghese, A., Cooper, A. A. , Swan, H., PÄIVI J. LAITINEN-FORSBLOM, MARK I. REES, JONATHAN R. SKINNER, TERENCE J. CAMPBELL, and JAMIE I. VANDENBERG, (2009). Not All hERG Pore Domain Mutations Have a Severe Phenotype: G584S Has an Inactivation Gating Defect with Mild Phenotype Compared to G572S, Which Has a Dominant Negative Trafficking Defect and a Severe Phenotype. Journal of Cardiovascular Electrophysiology, 20, 923-930.

  • Weir, E. K., Obreztchikova, M., Varghese, A., Cabrera, J. A. , Peterson, D. A. , Z Hong, (2008). Mechanisms of oxygen sensing: a key to therapy of pulmonary hypertension and patent ductus arteriosus. British Journal of Pharmacology.

  • Otway, R., Vandenberg, J. I., Guo, G., Varghese, A., & Castro, L. M. (2007). Stretch-Sensitive KCNQ1 Mutation. Journal of the American College of Cardiology. 
Articles in Proceedings
  • Hill, A. P., Varghese, A., Dokos, S., Mann, S., & Vandenberg, J. I. (in press, 2009). Developing In Silico Descriptions Of Herg Channel Gating. Biophysical Society Meeting, 96 (3 Suppl 1), Elsevier Inc., 191a.
Through Visual Paradigm Academic Partner Program, University of Wisconsin-River Falls is granted license for modeling software - VP-UML, Logizian for educational use.